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Vaccine in the process of transportation, preservation, restricted by conditions, under the county and epidemic prevention agencies equipped with refrigerator, rarely use vacuum flask or incubator, more difficult to avoid heat transport, sometimes suddenly high or low temperature, influence the effect of vaccine. Recent vaccine event, is the cold chain transportation problems lead to the vaccine failure, lead to tragedy.

The personage inside course of study says, compared with the provincial center for disease control and prevention, grassroots vaccine distribution problem a lot. Shanxi Province center for disease control and prevention in 2004, according to a study published report in the province's 93 counties surveyed, nearly thirty percent of the county cold-chain system will not operate properly, do not conform to the requirements of the cold chain transport vaccine transportation vehicles.

One industry source said, some pharmaceutical companies with the third party logistics distribution of vaccine, small logistics company lack of vaccines must be the consciousness of the cold chain transportation, and affected by the distribution cost factor, it is difficult to guarantee the cold-chain transport. If you use a refrigerator, an open air conditioning, fuel consumption is very high, increase the cost, some shipping companies.